Environmental Factors Related to Multiple Sclerosis in Indian Population

Chaithra Malli, Lekha Pandit, Anita D’Cunha and Sharik Mustafa

PLOS ONE, 2015, vol. 10, issue 4, 1-7

Abstract: Background: Multiple sclerosis (MS) is less prevalent among Indians when compared to white populations. Genetic susceptibility remaining the same it is possible that environmental associations may have a role in determining disease prevalence. Aims: To determine whether childhood infections, vaccination status, past infection with Helicobacter pylori (H.pylori), diet, socioeconomic and educational status were associated with MS. Material and Methods: 139 patients and 278 matched control subjects were selected. A validated environmental exposure questionnaire was administered. Estimation of serum H.pylori IgG antibody was done by ELISA. Patients and controls were genotyped for HLA-DRB1*15:01. Results: In our cohort a significant association was seen with measles (p

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0124064

DOI: 10.1371/journal.pone.0124064

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