A Context-Aware Delayed Agglomeration Framework for Electron Microscopy Segmentation

Toufiq Parag, Anirban Chakraborty, Stephen Plaza and Louis Scheffer

PLOS ONE, 2015, vol. 10, issue 5, 1-19

Abstract: Electron Microscopy (EM) image (or volume) segmentation has become significantly important in recent years as an instrument for connectomics. This paper proposes a novel agglomerative framework for EM segmentation. In particular, given an over-segmented image or volume, we propose a novel framework for accurately clustering regions of the same neuron. Unlike existing agglomerative methods, the proposed context-aware algorithm divides superpixels (over-segmented regions) of different biological entities into different subsets and agglomerates them separately. In addition, this paper describes a “delayed” scheme for agglomerative clustering that postpones some of the merge decisions, pertaining to newly formed bodies, in order to generate a more confident boundary prediction. We report significant improvements attained by the proposed approach in segmentation accuracy over existing standard methods on 2D and 3D datasets.

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0125825

DOI: 10.1371/journal.pone.0125825

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