Inverted U-Shaped Relationship between Central Venous Pressure and Intra-Abdominal Pressure in the Early Phase of Severe Acute Pancreatitis: A Retrospective Study

Chong Yang, Zhiyong Yang, Xinglin Chen, Tao Liu, Shanmiao Gou, Changzhong Chen, Jun Xiao, Xin Jin, Zhiqiang He, Liming Dong, Yushun Zhang, Na Luo, Heshui Wu and Chunyou Wang

PLOS ONE, 2015, vol. 10, issue 6, 1-12

Abstract: Objective: Many studies have indicated that intra-abdominal pressure (IAP) is positively correlated with central venous pressure (CVP) in severe cases. However, although elevated IAP is common in patients with severe acute pancreatitis (SAP), its relationship with CVP remains unclear. Our study aimed to investigate the association of IAP with CVP in early-phase SAP patients. Methods: In total, 116 SAP patients were included in this retrospective study. On the first day of hospitalization, blood samples were collected for biochemical examination and cytokine concentration monitoring. Additionally, a urinary catheter and right subclavian vein catheter were inserted for IAP and CVP measurement, respectively. Other routine clinical data were also recorded. Results: Within 24 hours after hospitalization, CVP fluctuated and increased with increasing IAP up to 15.7 mmHg (P = 0.054) but decreased with increasing IAP when the IAP was > 15.7 mmHg (P

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0128493

DOI: 10.1371/journal.pone.0128493

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