Serum Level of Fibroblast Growth Factor 21 Is Independently Associated with Acute Myocardial Infarction

Wenduo Zhang, Songyun Chu, Wenhui Ding and Fang Wang

PLOS ONE, 2015, vol. 10, issue 6, 1-9

Abstract: Background: Fibroblast growth factor 21 (FGF21) has been described as a metabolic hormone critical for glucose and lipid metabolism. Previously, high levels of FGF21 were observed in patients with coronary heart disease and non-acute myocardial infarction (non-AMI). In this study, we investigated the changes in FGF21 levels in Chinese patients with AMI. Methodology/Principal Findings: We used ELISA to measure circulating FGF21 levels in 55 AMI patients and 45 non-AMI control patients on the 1st day after syndrome onset. All patients were followed-up within 30 days. FGF21 levels in AMI patients were significantly higher than those in non-AMI controls (0.25 (0.16–0.34) vs. 0.14 (0.11–0.20) ng/mL, P

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0129791

DOI: 10.1371/journal.pone.0129791

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