Meta-Analysis Comparing Zero-Profile Spacer and Anterior Plate in Anterior Cervical Fusion

Jun Dong, Meng Lu, Teng Lu, Baobao Liang, Junkui Xu, Jun Zhou, Hongjun Lv, Jie Qin, Xuan Cai, Sihua Huang, Haopeng Li, Dong Wang and Xijing He

PLOS ONE, 2015, vol. 10, issue 6, 1-18

Abstract: Background: Anterior plate fusion is an effective procedure for the treatment of cervical spinal diseases but is accompanied by a high incidence of postoperative dysphagia. A zero profile (Zero-P) spacer is increasingly being used to reduce postoperative dysphagia and other potential complications associated with surgical intervention. Studies comparing the Zero-P spacer and anterior plate have reported conflicting results. Methodology: A meta-analysis was conducted to compare the safety, efficacy, radiological outcomes and complications associated with the use of a Zero-P spacer versus an anterior plate in anterior cervical spine fusion for the treatment of cervical spinal disease. We comprehensively searched PubMed, Embase, the Cochrane Library and other databases and performed a meta-analysis of all randomized controlled trials (RCTs) and prospective or retrospective comparative studies assessing the two techniques. Results: Ten studies enrolling 719 cervical spondylosis patients were included. The pooled data showed significant differences in the operation time [SMD = –0.58 (95% CI = −0.77 to 0.40, p

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0130223

DOI: 10.1371/journal.pone.0130223

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