High Mannose-Binding Lectin Serum Levels Are Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes

Qian Huang, Guilian Shang, Haohua Deng, Jie Liu, Yan Mei and Yancheng Xu

PLOS ONE, 2015, vol. 10, issue 7, 1-12

Abstract: Objective: To investigate mannose-binding lectin (MBL) serum levels in type 2 diabetic patients with and without diabetic retinopathy (DR). Methods: Serum MBL levels were determined in type 2 diabetic patients (N=324) as well as in 300 healthy control Subjects. Multivariate analyses were performed using logistic regression models. Receiver operating characteristic curves (ROC) was used to test the overall predict accuracy of MBL and other markers. Results: Diabetic patients with DR and vision-threatening diabetic retinopathy (VTDR) had significantly higher MBL levels on admission (P

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0130665

DOI: 10.1371/journal.pone.0130665

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