Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Platinum Chemotherapy in Muscle Invasive Urothelial Carcinoma

Alexander S Baras, Nilay Gandhi, Enrico Munari, Sheila Faraj, Luciana Shultz, Luigi Marchionni, Mark Schoenberg, Noah Hahn, Mohammad Hoque, David Berman, Trinity J Bivalacqua and George Netto

PLOS ONE, 2015, vol. 10, issue 7, 1-11

Abstract: Background: The 5-year cancer specific survival (CSS) for patients with muscle invasive urothelial carcinoma of the bladder (MIBC) treated with cystectomy alone is approximately 50%. Platinum based neoadjuvant chemotherapy (NAC) plus cystectomy results in a marginal 5-10% increase in 5-year CSS in MIBC. Interestingly, responders to NAC (

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0131245

DOI: 10.1371/journal.pone.0131245

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