Increased Circulating Cathepsin K in Patients with Chronic Heart Failure

Guangxian Zhao, Yuzi Li, Lan Cui, Xiang Li, Zhenyi Jin, Xiongyi Han, Ennan Fang, Yihua Gao, Dongmei Zhou, Haiying Jiang, Xueying Jin, Guanghao Piao, Xiangshan Li, Guang Yang, Jiyong Jin, Enbo Zhu, Meina Piao, Limei Piao, Kuichang Yuan, Yanna Lei, Dazhi Ding, Chengzhi Jin, Yongshan Nan and Xianwu Cheng

PLOS ONE, 2015, vol. 10, issue 8, 1-11

Abstract: Cysteinyl cathepsin K (CatK) is one of the most potent mammalian collagenases involved in cardiovascular disease. Here, we investigated the clinical predictive value of serum CatK levels in patients with chronic heart failure (CHF). We examined 134 patients with CHF, measuring their serum CatK, troponin I, high-sensitive C-reactive protein, and pre-operative N-terminal pro-brain natriuretic peptide levels. The patients were divided into two groups: the 44 patients who showed a left ventricular (LV) ejection fraction (LVEF)

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0136093

DOI: 10.1371/journal.pone.0136093

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