Biodiversity, Anti-Trypanosomal Activity Screening, and Metabolomic Profiling of Actinomycetes Isolated from Mediterranean Sponges

Cheng Cheng, Lynsey MacIntyre, Usama Ramadan Abdelmohsen, Hannes Horn, Paraskevi N Polymenakou, RuAngelie Edrada-Ebel and Ute Hentschel

PLOS ONE, 2015, vol. 10, issue 9, 1-21

Abstract: Marine sponge–associated actinomycetes are considered as promising sources for the discovery of novel biologically active compounds. In the present study, a total of 64 actinomycetes were isolated from 12 different marine sponge species that had been collected offshore the islands of Milos and Crete, Greece, eastern Mediterranean. The isolates were affiliated to 23 genera representing 8 different suborders based on nearly full length 16S rRNA gene sequencing. Four putatively novel species belonging to genera Geodermatophilus, Microlunatus, Rhodococcus and Actinomycetospora were identified based on a 16S rRNA gene sequence similarity of

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0138528

DOI: 10.1371/journal.pone.0138528

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