Reconstructing the Rasch-Built Myotonic Dystrophy Type 1 Activity and Participation Scale

Mieke C E Hermans, Janneke G J Hoeijmakers, Catharina G Faber and Ingemar S J Merkies

PLOS ONE, 2015, vol. 10, issue 10, 1-9

Abstract: Introduction: A previously published Rasch-built activity and participation scale specifically designed for patients with myotonic dystrophy type 1 (DM1) was criticized for having been constructed in a relatively small cohort of patients and containing items too broadly phrased for DM1 patients, thus hampering its clinical use. Methods: We report the results of the reconstructed Rasch-built DM1 activity and participation scale for clinical use (DM1-ActivC) through Rasch analyses using an expanded questionnaire containing 146 more simply phrased activity and participation inquiries completed by 340 patients with DM1. Results: Through stepwise investigation including data quality control, model fit, response category ordering, local dependency and item bias, we succeeded in reconstructing the DM1-ActivC consisting of 25 items that showed good Rasch model fit, including construct convergent validity, items’ weights and persons’ locations reliability, and unidimensionality. Conclusion: The DM1-ActivC scale has been reconstructed and fulfills all modern clinimetric requirements. Its use is recommended in future longitudinal trials in patients with DM1 to determine its responsiveness.

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0139944

DOI: 10.1371/journal.pone.0139944

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