Quantitative CT Imaging of Ventral Hernias: Preliminary Validation of an Anatomical Labeling Protocol

Zhoubing Xu, Andrew J Asman, Rebeccah B Baucom, Richard G Abramson, Benjamin K Poulose and Bennett A Landman

PLOS ONE, 2015, vol. 10, issue 10, 1-17

Abstract: Objective: We described and validated a quantitative anatomical labeling protocol for extracting clinically relevant quantitative parameters for ventral hernias (VH) from routine computed tomography (CT) scans. This information was then used to predict the need for mesh bridge closure during ventral hernia repair (VHR). Methods: A detailed anatomical labeling protocol was proposed to enable quantitative description of VH including shape, location, and surrounding environment (61 scans). Intra- and inter-rater reproducibilities were calculated for labeling on 18 and 10 clinically acquired CT scans, respectively. Preliminary clinical validation was performed by correlating 20 quantitative parameters derived from anatomical labeling with the requirement for mesh bridge closure at surgery (26 scans). Prediction of this clinical endpoint was compared with similar models fit on metrics from the semi-quantitative European Hernia Society Classification for Ventral Hernia (EHSCVH). Results: High labeling reproducibilities were achieved for abdominal walls (±2 mm in mean surface distance), key anatomical landmarks (±5 mm in point distance), and hernia volumes (0.8 in Cohen’s kappa). 9 out of 20 individual quantitative parameters of hernia properties were significantly different between patients who required mesh bridge closure versus those in whom fascial closure was achieved at the time of VHR (p

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0141671

DOI: 10.1371/journal.pone.0141671

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