Antiretroviral Therapy, Especially Efavirenz, Is Associated with Low Bone Mineral Density in HIV-Infected South Africans

Joel A Dave, Karen Cohen, Lisa K Micklesfield, Gary Maartens and Naomi S Levitt

PLOS ONE, 2015, vol. 10, issue 12, 1-9

Abstract: Purpose: We determined the prevalence and correlates of low bone mineral density (BMD) in HIV-infected South Africans as there is a paucity of such data from Africa. Methods: BMD and serum 25-hydroxyvitamin D were measured in HIV-positive participants on antiretroviral therapy (ART) and in those not yet on ART (ART-naïve). Results: We enrolled 444 participants [median age 35(IQR: 30, 40) years; 77% women]. BMD was low (z score

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0144286

DOI: 10.1371/journal.pone.0144286

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