Clinical Correlates of Mass Effect in Autosomal Dominant Polycystic Kidney Disease

Hyunsuk Kim, Hayne Cho Park, Hyunjin Ryu, Kiwon Kim, Hyo Sang Kim, Kook-Hwan Oh, Su Jong Yu, Jin Wook Chung, Jeong Yeon Cho, Seung Hyup Kim, Hae Il Cheong, Kyubeck Lee, Jong Hoon Park, York Pei, Young-Hwan Hwang and Curie Ahn

PLOS ONE, 2015, vol. 10, issue 12, 1-14

Abstract: Mass effect from polycystic kidney and liver enlargement can result in significant clinical complications and symptoms in autosomal dominant polycystic kidney disease (ADPKD). In this single-center study, we examined the correlation of height-adjusted total liver volume (htTLV) and total kidney volume (htTKV) by CT imaging with hepatic complications (n = 461) and abdominal symptoms (n = 253) in patients with ADPKD. “Mass-effect” complications were assessed by review of medical records and abdominal symptoms, by a standardized research questionnaire. Overall, 91.8% of patients had 4 or more liver cysts on CT scans. Polycystic liver disease (PLD) was classified as none or mild (htTLV

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0144526

DOI: 10.1371/journal.pone.0144526

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