Body Mass Index Is Associated with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

Jie Dong, Yi Chen, Yuchen Tang, Fei Xu, Chaohui Yu, Youming Li, Prasoon Pankaj and Ning Dai

PLOS ONE, 2015, vol. 10, issue 12, 1-19

Abstract: Background: Prior work suggested that patients with inflammatory bowel diseases (IBD) have lower body mass index (BMI) than controls and patients with lower BMI have more serious complications. Goal: The study was aimed to find relationship between BMI in patients with and without IBD, investigate effects of medicine therapy and disease stages on patients’ BMI. Methods: Potentially eligible studies were identified through searching PubMed, Cochrane and Embase databases. Outcome measurements of mean BMI and the number of patients from each study were pooled by a random-effect model. Publication bias test, sensitivity analysis and subgroup analysis were conducted. Results: A total of 24 studies containing 1442 patients and 2059 controls were included. Main results were as follows: (1) BMI in Crohn’s disease (CD) patients was lower than that in health controls (-1.88, 95% CI -2.77 to -1.00, P

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0144872

DOI: 10.1371/journal.pone.0144872

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