Highly Predictive Model for a Protective Immune Response to the A(H1N1)pdm2009 Influenza Strain after Seasonal Vaccination

Karsten Jürchott, Axel Ronald Schulz, Cecilia Bozzetti, Dominika Pohlmann, Ulrik Stervbo, Sarah Warth, Julia Nora Mälzer, Julian Waldner, Brunhilde Schweiger, Sven Olek, Andreas Grützkau, Nina Babel, Andreas Thiel and Avidan Uriel Neumann

PLOS ONE, 2016, vol. 11, issue 3, 1-22

Abstract: Understanding the immune response after vaccination against new influenza strains is highly important in case of an imminent influenza pandemic and for optimization of seasonal vaccination strategies in high risk population groups, especially the elderly. Models predicting the best sero-conversion response among the three strains in the seasonal vaccine were recently suggested. However, these models use a large number of variables and/or information post- vaccination. Here in an exploratory pilot study, we analyzed the baseline immune status in young (

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0150812

DOI: 10.1371/journal.pone.0150812

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