Determinants of Slow Walking Speed in Ambulatory Patients Undergoing Maintenance Hemodialysis

Yoshifumi Abe, Atsuhiko Matsunaga, Ryota Matsuzawa, Toshiki Kutsuna, Shuhei Yamamoto, Kei Yoneki, Manae Harada, Ryoma Ishikawa, Takaaki Watanabe and Atsushi Yoshida

PLOS ONE, 2016, vol. 11, issue 3, 1-15

Abstract: Walking ability is significantly lower in hemodialysis patients compared to healthy people. Decreased walking ability characterized by slow walking speed is associated with adverse clinical events, but determinants of decreased walking speed in hemodialysis patients are unknown. The purpose of this study was to identify factors associated with slow walking speed in ambulatory hemodialysis patients. Subjects were 122 outpatients (64 men, 58 women; mean age, 68 years) undergoing hemodialysis. Clinical characteristics including comorbidities, motor function (strength, flexibility, and balance), and maximum walking speed (MWS) were measured and compared across sex-specific tertiles of MWS. Univariate and multivariate logistic regression analyses were performed to examine whether clinical characteristics and motor function could discriminate between the lowest, middle, and highest tertiles of MWS. Significant and common factors that discriminated the lowest and highest tertiles of MWS from other categories were presence of cardiac disease (lowest: odds ratio [OR] = 3.33, 95% confidence interval [CI] = 1.26–8.83, P

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0151037

DOI: 10.1371/journal.pone.0151037

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