microRNA Profiling of Amniotic Fluid: Evidence of Synergy of microRNAs in Fetal Development

Tingting Sun, Weiyun Li, Tianpeng Li and Shucai Ling

PLOS ONE, 2016, vol. 11, issue 5, 1-15

Abstract: Amniotic fluid (AF) continuously exchanges molecules with the fetus, playing critical roles in fetal development especially via its complex components. Among these components, microRNAs are thought to be transferred between cells loaded in microvesicles. However, the functions of AF microRNAs remain unknown. To date, few studies have examined microRNAs in amniotic fluid. In this study, we employed miRCURY Locked Nucleotide Acid arrays to profile the dynamic expression of microRNAs in AF from mice on embryonic days E13, E15, and E17. At these times, 233 microRNAs were differentially expressed (p

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0153950

DOI: 10.1371/journal.pone.0153950

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