Effect of Patient Sex on the Severity of Coronary Artery Disease in Patients with Newly Diagnosis of Obstructive Sleep Apnoea Admitted by an Acute Coronary Syndrome

Alicia Sánchez- de-la-Torre, Jorge Abad, Joaquín Durán-Cantolla, Olga Mediano, Valentín Cabriada, María José Masdeu, Joaquín Terán, Juan Fernando Masa, Mónica de la Peña, Albina Aldomá, Fernando Worner, Joan Valls, Ferran Barbé, Manuel Sánchez- de-la-Torre and Spanish Sleep Group

PLOS ONE, 2016, vol. 11, issue 7, 1-12

Abstract: Background: The cardiovascular consequences of obstructive sleep apnoea (OSA) differ by sex. We hypothesized that sex influences the severity of acute coronary syndrome (ACS) in patients with OSA. OSA was defined as an apnoea–hypopnoea index (AHI)>15 events·h-1. We evaluated the severity of ACS according to the ejection fraction, Killip class, number of diseased vessels, number of stents implanted and plasma peak troponin level. Methods: We included 663 men (mean±SD, AHI 37±18 events·h-1) and 133 women (AHI 35±18 events·h-1) with OSA. Results: The men were younger than the women (59±11 versus 66±11 years, p

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0159207

DOI: 10.1371/journal.pone.0159207

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