Serum 25–Hydroxyvitamin D3 and Mammography Density among Mexican Women

Amina Amadou, Carine Biessy, Sabina Rinaldi, Veronika Fedirko, Nada Assi, Martin Lajous, Eduardo Ortiz-Panozo, Elsa Yunes, Ruy Lopez-Ridaura, Gabriela Torres-Mejia and Isabelle Romieu

PLOS ONE, 2016, vol. 11, issue 8, 1-14

Abstract: Low circulating levels of vitamin D and high mammographic density (MD) have been associated with higher risk of breast cancer. Although some evidence suggested an inverse association between circulating vitamin D and MD, no studies have investigated this association among Mexican women. We examined whether serum 25−hydroxyvitamin D3 [25(OH)D3] levels were associated with MD in a cross-sectional study nested within the large Mexican Teacher's Cohort. This study included 491 premenopausal women with a mean age of 42.9 years. Serum 25(OH)D3 levels were measured by liquid chromatography/tandem mass spectrometry. Linear regression and non-linear adjusted models were used to estimate the association of MD with serum 25(OH)D3. Median serum 25(OH)D3 level was 27.3 (23.3–32.8) (ng/ml). Forty one (8%) women had 25(OH)D3 levels in the deficient range (

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0161686

DOI: 10.1371/journal.pone.0161686

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