Comparison of the Association of Excess Weight on Health Related Quality of Life of Women with Polycystic Ovary Syndrome: An Age- and BMI-Matched Case Control Study

Farnaz Shishehgar, Fahimeh Ramezani Tehrani, Parvin Mirmiran, Sepideh Hajian and Ahmad Reza Baghestani

PLOS ONE, 2016, vol. 11, issue 10, 1-11

Abstract: Background: It is assumed that obesity adversely affects the health related quality of life (HRQOL) of women with polycystic ovary syndrome (PCOS), not only due to the excess weight, but also due to several other obesity induced metabolic and reproductive consequences. We aimed to compare the effects of excess body weight on the HRQOL between women with PCOS and controls. Methods: This is a case control study of 142 women with PCOS and 140 age- and BMI- matched controls. The Iranian version of short form health survey 36 (SF 36) was used to assess HRQOL. Domains of SF 36 were compared in women with PCOS and controls using multivariate analysis of covariance. The Pearson correlation was used to assess the correlation between body mass index (BMI) and domain scores of SF 36, and the differences between two correlations in cases and controls, using Fisher’s Z test. Results: Women with PCOS had significantly lower scores for both, the physical and the mental component summary scales, compared to controls. In the cases, a significant negative correlations were observed for BMI with physical function (r = - 0.301, P

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0162911

DOI: 10.1371/journal.pone.0162911

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