Circulating microRNAs in patients with intracranial aneurysms
John A L Meeuwsen,
Femke N G van ´t Hof,
Wouter van Rheenen,
Gabriel J E Rinkel,
Jan H Veldink and
Ynte M Ruigrok
PLOS ONE, 2017, vol. 12, issue 5, 1-11
Abstract:
Introduction: We compared circulating microRNA (miRNA) levels in plasma of patients with intracranial aneurysms (IA) to those of controls as a first step towards finding potential biomarkers for individuals at high risk of IA development and its subsequent rupture. Patients and methods: Using a PCR array we measured 370 miRNAs in plasma of 15 patients with prior aneurysmal subarachnoid hemorrhage (aSAH), of whom 11 had an additional unruptured IA (UIA), and of 15 controls. MiRNAs with a difference in levels with an absolute fold change (FC) > 1.2 and p 1.2 and p
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0176558
DOI: 10.1371/journal.pone.0176558
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