Associations between MRI features versus knee pain severity and progression: Data from the Vancouver Longitudinal Study of Early Knee Osteoarthritis

Eric C Sayre, Ali Guermazi, John M Esdaile, Jacek A Kopec, Joel Singer, Anona Thorne, Savvas Nicolaou and Jolanda Cibere

PLOS ONE, 2017, vol. 12, issue 5, 1-12

Abstract: Objective: To determine associations between features of osteoarthritis (OA) on MRI and knee pain severity and knee pain progression. Design: Baseline, 3.3- and 7.5-year assessments were performed for 122 subjects with baseline knee pain (age 40–79), sample-weighted for population (with knee pain) representativeness. MRIs were scored for: osteophytes (0:absent to 3:large); cartilage (0:normal to 4:full thickness defect; 0/1 collapsed); subchondral sclerosis (0:none to 3:>50% of site), subchondral cyst (0:absent to 3:severe), bone marrow lesions (0:none to 3:≥50% of site); and meniscus (0:normal to 3:maceration/resection), in 6–8 regions each. Per feature, scores were averaged across regions. Effusion/synovitis (0:absent to 3:severe) was analyzed as ≥2 vs.

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0176833

DOI: 10.1371/journal.pone.0176833

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