Drug-class-specific changes in the volume and cost of antidiabetic medications in Poland between 2012 and 2015

Andrzej Śliwczyński, Melania Brzozowska, Andrzej Jacyna, Petre Iltchev, Tymoteusz Iwańczuk, Waldemar Wierzba, Michał Marczak, Katarzyna Orlewska, Piotr Szymański and Ewa Orlewska

PLOS ONE, 2017, vol. 12, issue 6, 1-11

Abstract: Aim: to investigate the drug-class-specific changes in the volume and cost of antidiabetic medications in Poland in 2012–2015. Methods: This retrospective analysis was conducted based on the National Health Fund database covering an entire Polish population. The volume of antidiabetic medications is reported according to ATC/DDD methodology, costs—in current international dollars, based on purchasing power parity. Results: During a 4-year observational period the number of patients, consumption of antidiabetic drugs and costs increased by 17%, 21% and 20%, respectively. Biguanides are the basic diabetes medication with a 39% market share. The insulin market is still dominated by human insulins, new antidiabetics (incretins, thiazolidinediones) are practically absent. Insulins had the largest share in diabetes medications expenditures (67% in 2015). The increase in antidiabetic medications costs over the analysed period of time was mainly caused by the increased use of insulin analogues. Conclusions: The observed tendencies correspond to the evidence-based HTA recommendations. The reimbursement status, the ratio of cost to clinical outcomes and data on the long-term safety have a deciding impact on how a drug is used.

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0178764

DOI: 10.1371/journal.pone.0178764

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