Percutaneous coronary intervention in left main coronary artery disease with or without intravascular ultrasound: A meta-analysis

Yicong Ye, Ming Yang, Shuyang Zhang and Yong Zeng

PLOS ONE, 2017, vol. 12, issue 6, 1-13

Abstract: This meta-analysis compared IVUS-guided with angiography-guided PCI to determine the effect of IVUS on the mortality in patients with LM CAD. Current guidelines recommend intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) in patients with left main coronary artery disease (LM CAD; Class IIa, level of evidence B). A systematic search of the MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases was conducted to identify randomized or non-randomized studies comparing IVUS-guided PCI with angiography-guided PCI in LM CAD. Ten studies (9 non-randomized and 1 randomized) with 6,480 patients were included. The primary outcome was mortality including all-cause death and cardiac death. Compared with angiography-guide PCI, IVUS-guided PCI was associated with significantly lower risks of all-cause death (risk ratio [RR] 0.60, 95% confidence interval [CI] 0.47–0.75, p

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0179756

DOI: 10.1371/journal.pone.0179756

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