Maternal 25(OH)D concentrations ≥40 ng/mL associated with 60% lower preterm birth risk among general obstetrical patients at an urban medical center

Sharon L McDonnell, Keith A Baggerly, Carole A Baggerly, Jennifer L Aliano, Christine B French, Leo L Baggerly, Myla D Ebeling, Charles S Rittenberg, Christopher G Goodier, Julio F Mateus Niño, Rebecca J Wineland, Roger B Newman, Bruce W Hollis and Carol L Wagner

PLOS ONE, 2017, vol. 12, issue 7, 1-12

Abstract: Background: Given the high rate of preterm birth (PTB) nationwide and data from RCTs demonstrating risk reduction with vitamin D supplementation, the Medical University of South Carolina (MUSC) implemented a new standard of care for pregnant women to receive vitamin D testing and supplementation. Objectives: To determine if the reported inverse relationship between maternal 25(OH)D and PTB risk could be replicated at MUSC, an urban medical center treating a large, diverse population. Methods: Medical record data were obtained for pregnant patients aged 18–45 years between September 2015 and December 2016. During this time, a protocol that included 25(OH)D testing at first prenatal visit with recommended follow-up testing was initiated. Free vitamin D supplements were offered and the treatment goal was ≥40 ng/mL. PTB rates (

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0180483

DOI: 10.1371/journal.pone.0180483

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