Heart rate variability in multibacillar leprosy: Linear and nonlinear analysis

Marcio Clementino de Souza Santos, Luiz Carlos de Lima Silveira, Sílvia Cristina Garcia Moura-Tonello, Alberto Porta, Aparecida Maria Catai and Givago da Silva Souza

PLOS ONE, 2017, vol. 12, issue 7, 1-14

Abstract: Objective: To evaluate the heart rate variability (HRV) in patients with multibacillary leprosy using dynamic linear and nonlinear analysis. Material and methods: Twenty-one leprosy patients (mean age: 39.14 ±10.58 years) and 21 healthy subjects (mean age: 36.24 ± 12.64 years) completed the sample. Heart rate variability recording was performed by a Polar RS800 CX heart monitor during a period of 15 min in the supine position and 15 min in a sitting position. Analysis of HRV was performed by frequency domain from high frequency (HF) and low frequency (LF) spectral indexes in absolute and normalized units. The nonlinear analysis of HRV was calculated using symbolic analysis (0V%, 1V%, 2LV% and 2UV% indexes), Shannon entropy (SE) and normalized complexity index (NCI). Results: Linear analysis: both groups showed higher HF values (p

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0180677

DOI: 10.1371/journal.pone.0180677

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