Plantar pressures are elevated in people with longstanding diabetes-related foot ulcers during follow-up

Malindu E Fernando, Robert G Crowther, Peter A Lazzarini, Saiumaeswar Yogakanthi, Kunwarjit S Sangla, Petra Buttner, Rhondda Jones and Jonathan Golledge

PLOS ONE, 2017, vol. 12, issue 8, 1-17

Abstract: Objective: High plantar pressures are implicated in the development of diabetes-related foot ulcers. Whether plantar pressures remain high in patients with chronic diabetes-related foot ulcers over time is uncertain. The primary aim of this study was to compare plantar pressures at baseline and three and six months later in participants with chronic diabetes-related foot ulcers (cases) to participants without foot ulcers (controls). Methods: Standardised protocols were used to measure mean peak plantar pressure and pressure-time integral at 10 plantar foot sites (the hallux, toes, metatarsals 1 to 5, mid-foot, medial heel and lateral heel) during barefoot walking. Measurements were performed at three study visits: baseline, three and six months. Linear mixed effects random-intercept models were utilised to assess whether plantar pressures differed between cases and controls after adjusting for age, sex, body mass index, neuropathy status and follow-up time. Standardised mean differences (Cohen’s d) were used to measure effect size. Results: Twenty-one cases and 69 controls started the study and 16 cases and 63 controls completed the study. Cases had a higher mean peak plantar pressure at several foot sites including the toes (p = 0.005, Cohen’s d = 0.36) and mid-foot (p = 0.01, d = 0.36) and a higher pressure-time integral at the hallux (p

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0181916

DOI: 10.1371/journal.pone.0181916

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