Efficacy and safety of intravenous laronidase for mucopolysaccharidosis type I: A systematic review and meta-analysis

Alícia Dorneles Dornelles, Osvaldo Artigalás, André Anjos da Silva, Dora Lucia Vallejo Ardila, Taciane Alegra, Tiago Veiga Pereira, Filippo Pinto e Vairo and Ida Vanessa Doederlein Schwartz

PLOS ONE, 2017, vol. 12, issue 8, 1-18

Abstract: Objective: To evaluate the efficacy and safety of IV laronidase for MPS I. Methods: A systematic literature review was performed by searching the ClinicalTrials.gov, MEDLINE/PubMed, EMBASE, LILACS, and Cochrane Library databases, limited to clinical trials published until December 31, 2016. The first inclusion criterion was being a randomized controlled trial (RCT). If

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0184065

DOI: 10.1371/journal.pone.0184065

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