Immune response to hepatitis B vaccination in HIV-positive individuals with isolated antibodies against hepatitis B core antigen: Results of a prospective Italian study

Giulia Morsica, Sabrina Bagaglio, Vincenzo Spagnuolo, Antonella Castagna, Clelia Di Serio, Andrea Galli, Liviana Della Torre, Andrea Andolina, Alexander Pramov and Caterina Uberti-Foppa

PLOS ONE, 2017, vol. 12, issue 9, 1-10

Abstract: Background and aim: Antibodies against hepatitis B core antigen (anti-HBc) are found in 14–44% of patients with HIV infection, but it is still unclear whether hepatitis B virus (HBV) vaccination should be recommended for HIV-positive subjects with isolated anti-HBc (IAHBc). We examined the rate of anamnestic and primary responses (ARs and PRs) and associated factors in a group of HIV-infected patients with an IAHBc profile. Methods: This prospective study recruited 25 HIV-positive patients with anti-HBc alone who were vaccinated against HBV infection. Those without an AR (anti-hepatitis B envelope antigen [anti-HBs] levels of 10 but

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0184128

DOI: 10.1371/journal.pone.0184128

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