Hypothyroidism as a risk factor for open angle glaucoma: A systematic review and meta-analysis

Shiming Wang, Yue Liu and Guangying Zheng

PLOS ONE, 2017, vol. 12, issue 10, 1-13

Abstract: Purpose: The relationship between hypothyroidism and primary open angle glaucoma (POAG) has attracted intense interest recently, but the reported results have been controversial. This meta-analysis was carried out to determine the association between hypothyroidism and POAG. Methods: The literature was identified from three databases (Web of Science, Embase, and PubMed). The meta-analyses were performed using random-effects models, with results reported as adjusted odds ratios (ORs) with 95% confidence intervals (CI 95%). Results: A total of 11 studies meeting the inclusion criteria were included in the final meta-analysis. The pooled OR based on 11 risk estimates showed a statistically significant increased risk of POAG prevalence among individuals with hypothyroidism (OR = 1.64, 95% CI = 1.27–2.13). Substantial heterogeneity among these studies was detected (P

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0186634

DOI: 10.1371/journal.pone.0186634

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