Occult RV systolic dysfunction detected by CMR derived RV circumferential strain in patients with pectus excavatum

Vien T Truong, Candice Y Li, Rebeccah L Brown, Ryan A Moore, Victor F Garcia, Eric J Crotty, Michael D Taylor, Tam M N Ngo and Wojciech Mazur

PLOS ONE, 2017, vol. 12, issue 12, 1-10

Abstract: Aims: To investigate the right ventricular (RV) strain in pectus excavatum (PE) patients using cardiac magnetic resonance tissue tracking (CMR TT). Materials and methods: Fifty consecutive pectus excavatum patients, 10 to 32 years of age (mean age 15 ± 4 years), underwent routine cardiac magnetic resonance imaging (CMR) including standard measures of chest geometry and cardiac size and function. The control group consisted of 20 healthy patients with a mean age of 17 ± 5 years. RV longitudinal and circumferential strain magnitude was assessed by a dedicated RV tissue tracking software. Results: Fifty patients with images of sufficient quality were included in the analysis. The mean right and left ventricular ejection fractions were 55 ± 5% and 59 ± 4%. The RV global longitudinal strain was -21.88 ± 4.63%. The RV circumferential strain at base, mid-cavity and apex were -13.66 ± 3.09%, -11.31 ± 2.79%, -20.73 ± 3.45%, respectively. There was no statistically significant decrease in right ventricular or left ventricular ejection fraction between patients and controls (p > 0.05 for each). There was no significant difference in RV global longitudinal strain between two groups (-21.88 ± 4.63 versus -21.99 ± 3.58; p = 0.93). However, there was significant decrease in mid-cavity circumferential strain magnitude in pectus patients compared with controls (-11.31 ± 2.79 versus -16.19 ± 2.86; p

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0189128

DOI: 10.1371/journal.pone.0189128

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