Maximum walking speed in multiple sclerosis assessed with visual perceptive computing
Anuschka Grobelny,
Janina R Behrens,
Sebastian Mertens,
Karen Otte,
Sebastian Mansow-Model,
Theresa Krüger,
Elona Gusho,
Judith Bellmann-Strobl,
Friedemann Paul,
Alexander U Brandt and
Tanja Schmitz-Hübsch
PLOS ONE, 2017, vol. 12, issue 12, 1-13
Abstract:
Background: Gait is often impaired in people with multiple sclerosis (PwMS), but detailed assessment of gait impairment in research and care remains challenging. In a previous pilot study we reported the feasibility of visual perceptive computing (VPC) for gait assessment in PwMS using the Short Maximum Speed Walk (SMSW), which assesses gait on recording distances confined to less than 4 meters. Objective: To investigate the equivalence of SMSW to rater-based timed 25ft. walk (T25FW) in a large cohort of PwMS, and to investigate the association of SMSW-derived gait parameters with clinical disability, as well as subjective and objective gait impairment, in order to validate the SMSW as a quick and objective measure of clinical relevance possibly superior to T25FW. Methods: 95 PwMS and 60 healthy controls (HC) performed the SMSW using a VPC system with Microsoft Kinect. All participants received two immediate retests to establish test-retest-reliability. Both PwMS and HC performed the T25FW. PwMS were rated according to the Expanded Disability Status Scale (EDSS) and answered the 12-item Multiple Sclerosis Walking Scale (MSWS-12) as a measure of self-perceived walking impairment. Results: PwMS showed reduced average speed (p
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0189281
DOI: 10.1371/journal.pone.0189281
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