Clinical usefulness of the SAMe-TT2R2 score: A systematic review and simulation meta-analysis

Jasper H A van Miert, Sarah Bos, Nic J G M Veeger and Karina Meijer

PLOS ONE, 2018, vol. 13, issue 3, 1-13

Abstract: Background: Vitamin K antagonist (VKA) therapy is safer and more effective when patients have a high time within the therapeutic range and low international normalised ratio variability. The SAMe-TT2R2 score aims to identify those at risk for poor VKA control. Objectives: To evaluate the predictive value and clinical usefulness of the SAMe-TT2R2 score to identify those at risk for poor VKA control. Methods: We performed a systematic review in MEDLINE and Embase for original research papers assessing the SAMe-TT2R2’s relation to poor TTR. We performed a meta-analysis where scores ≥ 2 and ≥ 3 predicting TTR

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0194208

DOI: 10.1371/journal.pone.0194208

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