Early mortality among children and adults in antiretroviral therapy programs in Southwest Ethiopia, 2003–15

Hailay Abrha Gesesew, Paul Ward, Kifle Woldemichael and Lillian Mwanri

PLOS ONE, 2018, vol. 13, issue 6, 1-17

Abstract: Background: Several studies reported that the majority of deaths in HIV-infected people are documented in their early antiretroviral therapy (ART) follow-ups. Early mortality refers to death of people on ART for follow up period of below 24 months due to any cause. The current study assessed predictors of early HIV mortality in Southwest Ethiopia. Methods: We have conducted a retrospective analysis of 5299 patient records dating from June 2003- March 2015. To estimate survival time and compare the time to event among the different groups of patients, we used a Kaplan Meir curve and log-rank test. To identify mortality predictors, we used a cox regression analysis. We used SPSS-20 for all analyses. Results: A total of 326 patients died in the 12 years follow-up period contributing to 6.2% cumulative incidence and 21.7 deaths per 1000 person-year observations incidence rate. Eighty-nine percent of the total deaths were documented in the first two years follow up—an early-term ART follow up. Early HIV mortality rates among adults were 50% less in separated, divorced or widowed patients compared with never married patients, 1.6 times higher in patients with baseline CD4 count

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0198815

DOI: 10.1371/journal.pone.0198815

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