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Efficacy of Hank's balanced salt solution compared to other solutions in the preservation of the periodontal ligament. A systematic review and meta-analysis

Nathalia Carolina Fernandes Fagundes, Leonardo Oliveira Bittencourt, Marcela Baraúna Magno, Márcia Martins Marques, Lucianne Cople Maia and Rafael Rodrigues Lima

PLOS ONE, 2018, vol. 13, issue 7, 1-19

Abstract: This systematic review and meta-analysis (MA) aimed to verify the capacity of different storage media to preserve viability of periodontal ligament cells in comparison to Hank’s Balanced Salt Solution. The searches, selection process, data extraction and Risk of Bias control were conducted according to Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. Five MA were conducted to compare the cell viability between milk versus Hank's balanced salt solution (HBSS) in a dichotomous (1) or continuous (2) data model; tap water versus HBSS (3); medicinal herbals versus HBSS (4); and saline solution versus HBSS (5). 693 potentially studies were identified, with 18 studies included in the qualitative and 8 studies included in the quantitative analysis. Most of the articles presented a low risk of bias. HBSS medium showed a superior ratio of cell viability compared to tap water (RR 0.26; 95% CI [0.21, 0.32]; p

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0200467

DOI: 10.1371/journal.pone.0200467

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