Pancreatic cancer survival analysis defines a signature that predicts outcome

Pichai Raman, Ravikanth Maddipati, Kian Huat Lim and Aydin Tozeren

PLOS ONE, 2018, vol. 13, issue 8, 1-18

Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the US. Despite multiple large-scale genetic sequencing studies, identification of predictors of patient survival remains challenging. We performed a comprehensive assessment and integrative analysis of large-scale gene expression datasets, across multiple platforms, to enable discovery of a prognostic gene signature for patient survival in pancreatic cancer. PDAC RNA-Sequencing data from The Cancer Genome Atlas was stratified into Survival+ (>2-year survival) and Survival–(

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0201751

DOI: 10.1371/journal.pone.0201751

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