Adverse prognostic impact of splenectomy on survival in gastric carcinoma patients: Regression and propensity score matching analysis of 1074 patients

Oh Jeong, Ho Goon Kim, Seong Yeob Ryu, Young Kyu Park and Mi Ran Jung

PLOS ONE, 2018, vol. 13, issue 9, 1-13

Abstract: Backgrounds: Patients with proximal gastric carcinoma undergo total gastrectomy with concomitant splenectomy to ensure the complete removal of splenic hilar lymph nodes. However, the impact of splenectomy on survival remains uncertain. This study aimed to investigate the impact of splenectomy on survival among patients with gastric carcinoma. Methods: Of 1074 patients who underwent total gastrectomy for proximal gastric carcinoma between 2006 and 2014, 229 patients underwent concomitant splenectomy or pancreaticosplenectomy during surgery. We investigated the prognostic impact of splenectomy using a regression and propensity score matched model. Results: The splenectomy and non-splenectomy groups differed in many baseline characteristics, including tumor stage, and had respective crude 5-year survival rates of 55% and 81% (p

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0203820

DOI: 10.1371/journal.pone.0203820

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