Incidence rates of dysvascular lower extremity amputation changes in Northern Netherlands: A comparison of three cohorts of 1991-1992, 2003-2004 and 2012-2013

Behrouz Fard, Pieter U Dijkstra, Roy E Stewart and Jan H B Geertzen

PLOS ONE, 2018, vol. 13, issue 9, 1-12

Abstract: Objective: To analyze the incidence rates of dysvascular major lower extremity amputations (LEA) in Northern Netherlands in 2012–2013 compared to previous cohorts in 1991–1992 and 2003–2004. Design: Retrospective cohort study. Participants: Adults (N = 343) with first ever dysvascular LEA at ankle disarticulation or more proximal levels. The median age (interquartile range) was 74.2 years (64.5–81.9), 64% were male and 55% had been diagnosed with diabetes mellitus (DM). Main outcome measures: Crude and age-standardized incidence rates of major LEA per 100.000 person-years. Results: Crude incidence rate (IR) of first ever major LEA in 2012–2013 was 9.9 per 100.000 person-years, while the age-standardized IR was 7.7 per 100.000 person-years. A Poisson regression analysis showed that amputation rates among men were 2.3 times higher compared to women (95%CI 1.9–2.6), while in 2012–2013 the population aged >63 years had decreased amputation rates compared to 1991–1992. In the DM population the crude IR decreased from 142.6 per 100.000 person-years in 2003–2004 to 89.2 per 100.000 person-years in 2012–2013 (p

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0204623

DOI: 10.1371/journal.pone.0204623

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