Plasma neutrophil gelatinase-associated lipocalin is independently associated with left ventricular hypertrophy and diastolic dysfunction in patients with chronic kidney disease

Il Young Kim, June Hyun Kim, Min Jeong Kim, Dong Won Lee, Cheol Gu Hwang, Miyeun Han, Harin Rhee, Sang Heon Song, Eun Young Seong and Soo Bong Lee

PLOS ONE, 2018, vol. 13, issue 10, 1-12

Abstract: Background: Cardiovascular disease (CVD) is a leading cause of death in patients with chronic kidney disease (CKD). Left ventricular hypertrophy (LVH) and left ventricular diastolic dysfunction (LVDD) are known as predictors of CVD in these patients. Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker of acute kidney injury. Recently, elevated NGAL levels have been reported in patients with CVD. This study aimed to evaluate the association between plasma NGAL levels and LVH/LVDD in patients with CKD. Methods: This study included 332 patients with pre-dialysis CKD (estimated glomerular filtration rate (eGFR)

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0205848

DOI: 10.1371/journal.pone.0205848

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