The association of CHA2DS2-VASc score and carotid plaque in patients with non-valvular atrial fibrillation

Luxiang Shang, Yang Zhao, Mengjiao Shao, Huaxin Sun, Min Feng, Yaodong Li, Xianhui Zhou and Baopeng Tang

PLOS ONE, 2019, vol. 14, issue 2, 1-9

Abstract: Objective: The aim of this study was to assess the association between CHA2DS2-VASc score and carotid plaques in patients with non-valvular atrial fibrillation (NVAF). Methods: We conducted a retrospective study including 3,435 NVAF patients who underwent carotid ultrasound examinations from January 2015 to December 2017.We collected the clinical data on the medical records system. Chi-square trend test was used to analyze trends between the prevalence of carotid plaques with an increasing CHA2DS2-VASc score. Univariate and multivariate logistic regression was also used to assess the association between carotid plaques and CHA2DS2-VASc scores. The area under the receiver operating characteristic (ROC) curve (AUC) was used to determine the optimal cutoff points of different CHA2DS2-VASc scores in NVAF patients. Results: NVAF patients with carotid plaques had higher CHA2DS2-VASc scores compared with patients who did not have carotid plaques (3.01±1.36 vs. 2.55±1.28, P

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0210945

DOI: 10.1371/journal.pone.0210945

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