Plasma cytokine levels and the presence of colorectal cancer

Masaki Yamaguchi, Shin Okamura, Taiki Yamaji, Motoki Iwasaki, Shoichiro Tsugane, Vivek Shetty and Tomonobu Koizumi

PLOS ONE, 2019, vol. 14, issue 3, 1-13

Abstract: Background/Aims: Cancer-related activation of cytokine networks are central aspects of tumor development. The goal of the study was to examine the possibility of plasma cytokines for the screening of colorectal cancer (CRC). Methods: We carried out a multicenter, hospital-based case-control study in 66 adult Japanese patients with CRC and 87 healthy adult Japanese. A multiplex bead array immunoassay was used to examine 27 different plasma cytokines. Their association with the presence of CRC was evaluated by logistic regression analysis after adjusting for potential confounding factors. Results: Thirteen plasma cytokines were notably associated with the presence of CRC (p

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0213602

DOI: 10.1371/journal.pone.0213602

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