Outcomes of protease inhibitor-based antiretroviral therapy amongst children and associated-factors in Yaoundé, Cameroon

Anne Esther Njom Nlend, Cathya Ornella Guessong, Annie Carole Nga Motaze, Claudian Soffo, Paul Olivier Koki Ndombo, Lionel Tsambang and Joseph Fokam

PLOS ONE, 2019, vol. 14, issue 3, 1-10

Abstract: Background: There are limited data on protease inhibitor (PI)-based antiretroviral therapy (ART) amongst children in resource-limited settings, for informing on optimal paediatric regimens. Objective: To evaluate therapeutic response to PI-based ART amongst HIV-infected Cameroonian children. Methods: A retrospective study was conducted amongst children aged 2–18 years receiving a PI-based ART at the Essos Hospital Centre (EHC), Yaounde, Cameroon. Primary end points were therapeutic success on PI-based ART, defined as clinical success (WHO I/II clinical stage), immunological success (CD4 ≥ 500/mm3) and viral suppression (viral load [VL]

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0213900

DOI: 10.1371/journal.pone.0213900

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