The prognostic value of CXC subfamily ligands in stage I-III patients with colorectal cancer

Xiangde Li, Qiulu Zhong, Danjing Luo, Qinghua Du and Wenqi Liu

PLOS ONE, 2019, vol. 14, issue 4, 1-11

Abstract: Objective: To investigate the value of CXC subfamily ligands in stage I-III patients with colorectal cancer, in order to find a new predictor for CRC patients. Methods: We used Gene Expression Omnibus (GEO) database to collect the gene expression of CXC subfamily ligands and corresponding clinical data. The survival analysis was performed by "survival" package of Rsoftware. The CRC patients’ DFS and the relationship between the expression levels of CXC subfamily ligands were evaluated by the univariate Cox regression analysis. Results: By using microarray data, there were 14 CXC subfamily ligands identified from dataset GSE39582. Seven CXC subfamily ligands were significantly correlated with DFS in CRC patients. (p

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0214611

DOI: 10.1371/journal.pone.0214611

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