Risk factors for incident anemia of chronic diseases: A cohort study

Yun-Gyoo Lee, Yoosoo Chang, Jihoon Kang, Dong-Hoe Koo, Seung-Sei Lee, Seungho Ryu and Sukjoong Oh

PLOS ONE, 2019, vol. 14, issue 5, 1-11

Abstract: Objective: Anemia of chronic disease (ACD) refers to hypoproliferative anemia in the context of acute or chronic activation of the immune system. There is a paucity of prospective data addressing the risk factors for ACD development. An association between common chronic diseases and ACD was examined cross-sectionally and longitudinally. Method: A cohort of 265,459 healthy participants without ACD at baseline were prospectively followed annually or biennially. Results: During average follow-up period of 62 months, 4,906 participants developed ACD (incidence rate 3.58 per 1000 person-years). Multivariable-adjusted hazard ratio (HR) [95% confidence interval (CI)] for incident ACD comparing estimated glomerular filtration rate 30–60 and

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0216062

DOI: 10.1371/journal.pone.0216062

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