Comparison of bilateral and unilateral upper limb training in people with stroke: A systematic review and meta-analysis

Pei-ming Chen, Patrick W H Kwong, Claudia K Y Lai and Shamay S M Ng

PLOS ONE, 2019, vol. 14, issue 5, 1-21

Abstract: Background and objectives: Bilateral upper limb training (BULT) and unilateral upper limb training (UULT) are two effective strategies for the recovery of upper limb motor function after stroke. This meta-analysis aimed to compare the improvements in motor impairment and functional performances of people with stroke after BULT and UULT. Research design and methods: This systematic review and meta-analysis identified 21 randomized controlled trials (RCTs) met the eligibility criteria from CINAHL, Medline, Embase, Cochrane Library and PubMed. The outcome measures were the Fugl-Meyer Assessment of Upper Extremity (FMA-UE), Wolf Motor Function Test (WMFT), Action Research Arm Test (ARAT) and Box and Block Test (BBT), which are validated measures of upper limb function. Results: Twenty-one studies involving 842 subjects with stroke were included. Compared with UULT, BULT yielded a significantly greater mean difference (MD) in the FMA-UE (MD = 2.21, 95% Confidence Interval (CI), 0.12 to 4.30, p = 0.04; I2 = 86%, p

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0216357

DOI: 10.1371/journal.pone.0216357

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