Genome-wide analysis identifies rare copy number variations associated with inflammatory bowel disease

Svetlana Frenkel, Charles N Bernstein, Michael Sargent, Qin Kuang, Wenxin Jiang, John Wei, Bhooma Thiruvahindrapuram, Elizabeth Spriggs, Stephen W Scherer and Pingzhao Hu

PLOS ONE, 2019, vol. 14, issue 6, 1-16

Abstract: Background: Inflammatory bowel disease (IBD) is an idiopathic, chronic disorder of unclear etiology with an underlying genetic predisposition. Recent genome-wide association studies have identified more than 200 IBD susceptibility loci, but the causes of IBD remain poorly defined. We hypothesized that rare (

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0217846

DOI: 10.1371/journal.pone.0217846

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