The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study

Georgios Karamanakos, Bernardo Costa-Pinel, Aleksandra Gilis-Januszewska, Dzilda Velickiene, Francisco Barrio-Torrell, Xavier Cos-Claramunt, Santiago Mestre-Miravet, Beata Piwońska-Solska, Alicja Hubalewska-Dydejczyk, Jaakko Tuomilehto, Stavros Liatis and Konstantinos Makrilakis

PLOS ONE, 2019, vol. 14, issue 10, 1-17

Abstract: Background and aims: The DE-PLAN was a European multicenter study, with the primary objective of testing whether a community-based lifestyle modification programme could serve as a means of primary prevention for type 2 diabetes (T2D) in high-risk individuals (based on the FINDRISC questionnaire). The aim of this study was to examine the impact of a 1-year community-based lifestyle intervention on health-related quality of life (HRQOL) in individuals from four participating European centers (Athens, Barcelona, Krakow, Kaunas), through a post-hoc analysis. Materials and methods: Each center was allowed to implement different intervention strategies specifically tailored to the needs of their corresponding population sample. Before and after the intervention, participants underwent clinical evaluation, anthropometric measurements, an oral glucose tolerance test and lipid profile measurements. Health-related quality of life was assessed using the validated HRQOL-15D questionnaire. A difference of ±0.015 in the 15D questionnaire score was set as the threshold of clinically meaningful change. Results: Data from 786 participants (67% females, mean age 59.7±9.4 years, BMI 31.5±4.5 kg/m2) with complete data regarding the HRQOL were analyzed (Athens: 104, Barcelona: 434, Krakow: 175, Kaunas: 70). After 1 year, a significant overall improvement in HRQOL was shown, as depicted by a change of 15D score from baseline value (0.88±0.9) to post-intervention (0.90±0.87, P

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0221467

DOI: 10.1371/journal.pone.0221467

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