Repeated noninvasive stimulation of the ventromedial prefrontal cortex reveals cumulative amplification of pleasant compared to unpleasant scene processing: A single subject pilot study

Constantin Winker, Maimu A Rehbein, Dean Sabatinelli and Markus Junghofer

PLOS ONE, 2020, vol. 15, issue 1, 1-11

Abstract: The ventromedial prefrontal cortex (vmPFC) is a major hub of the reward system and has been shown to activate specifically in response to pleasant / rewarding stimuli. Previous studies demonstrate enhanced pleasant cue reactivity after single applications of transcranial direct current stimulation (tDCS) to the vmPFC. Here we present a pilot case study in which we assess the cumulative impact of multiple consecutive vmPFC-tDCS sessions on the processing of visual emotional stimuli in an event-related MEG recording design. The results point to stable modulation of increased positivity biases (pleasant > unpleasant stimulus signal strength) after excitatory vmPFC stimulation and a reversed pattern (pleasant

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0222057

DOI: 10.1371/journal.pone.0222057

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