Risk factors associated with IgA vasculitis with nephritis (Henoch–Schönlein purpura nephritis) progressing to unfavorable outcomes: A meta-analysis

Dongmei Shi, Han Chan, Xia Yang, Gaofu Zhang, Haiping Yang, Mo Wang and Qiu Li

PLOS ONE, 2019, vol. 14, issue 10, 1-15

Abstract: Objective: To identify risk factors associated with unfavorable outcomes in children with IgA vasculitis with nephritis (Henoch-Schőnlein purpura nephritis)(IgA-VN) Methods: PubMed, Embase, and Web of Science databases were searched for studies, published in English through February 2019. The data were extracted to perform pooled analysis, heterogeneity testing, subgroup analysis, sensitivity analysis, and publication bias analysis. Results: This meta-analysis showed that, older age at onset (WMD 1.77, 95% CI 0.35–3.18, p = 0.014), lower glomerular filtration rate (GFR; WMD -23.93, 95% CI -33.78- -14.09, p

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0223218

DOI: 10.1371/journal.pone.0223218

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