Effects of dietary intake and nutritional status on cerebral oxygenation in patients with chronic kidney disease not undergoing dialysis: A cross-sectional study

Susumu Ookawara, Yoshio Kaku, Kiyonori Ito, Kanako Kizukuri, Aiko Namikawa, Shinobu Nakahara, Yuko Horiuchi, Nagisa Inose, Mayako Miyahara, Michiko Shiina, Saori Minato, Mitsutoshi Shindo, Haruhisa Miyazawa, Keiji Hirai, Taro Hoshino, Miho Murakoshi, Kaoru Tabei and Yoshiyuki Morishita

PLOS ONE, 2019, vol. 14, issue 10, 1-13

Abstract: Background: Dietary management is highly important for the maintenance of renal function in patients with chronic kidney disease (CKD). Cerebral oxygen saturation (rSO2) was reportedly associated with the estimated glomerular filtration rate (eGFR) and cognitive function. However, data concerning the association between cerebral rSO2 and dietary intake of CKD patients is limited. Methods: This was a single-center observational study. We recruited 67 CKD patients not undergoing dialysis. Cerebral rSO2 was monitored using the INVOS 5100c oxygen saturation monitor. Energy intake was evaluated by dietitians based on 3-day meal records. Daily protein and salt intakes were calculated from 24-h urine collection. Results: Multivariable regression analysis showed that cerebral rSO2 was independently associated with energy intake (standardized coefficient: 0.370) and serum albumin concentration (standardized coefficient: 0.236) in Model 1 using parameters with p

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0223605

DOI: 10.1371/journal.pone.0223605

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